High Throughput Screening (HTS) is now optimized using a 96 SCP Head. With the ability of independently controlling each tip with individual volumes and volume verification, an entire 96 well compound sample plate may be diluted and mixed in a single step. By using a worklist protocol method, it is now possible to take a compound plate that has an electronic file containing each wells compound, volume and concentration are used to calculate a corresponding amount of DMSO to dilute all the compounds to a standard concentration.
The 96 SCP Head can be used to dilute compound plates for a HTS assay in multiple high throughput ways:
In addition, the single channel independent tips may also perform any of the above tasks with the same performance and validation and is required for applications like hit picking for a secondary screen when individual well and / or tube access is required.