Air Based Microliter Pipetting

Seyonic Pipetting Technology

Seyonic’s Sensor Controlled Pipetting technology allows very precise monitoring of the liquid handling process. It thus provides not only accurate volume control but also detects pipetting errors in real time. Therefore every pipetting operation can effectively be validated as it is going on. The Process Control Diagnostics allow detection of partial or complete air aspiration while calculating the actually aspirated sample volume. In case of tip clogging, operation is halted immediately to permit the best possibility for recovery.
Process Control Diagnostics are based on analysis of changes in pipetting flow. It is therefore largerly independent of the volume or pipetting speed and does not need to establish guide band reference curves for every possible specific pipetting operation.

Benefits

Microliter/Milliliter Air Based System

Sensor Controlled Pipetting allows the active 'volumetric' monitoring of pipetting leading to more precise and validated liquid transfers
Factory calibrated 'out-of-box' pipetting
Reproducibility from tip to tip and platform to platform
Wide Dynamic range from 0.5 µL to 1 mL using the same device
Individual channel control
Active and continuous monitoring
No cross contamination with the use of disposable tips
Liquid level sensing with standard clear tips
Actually see the liquid in your tips, as opposed to black poly carbonate tips

Advantages

over microliter/milliliter liquid based systems

Reduced liquid class development
No dilution effects from fluid filled microliter/milliliter systems
No hydraulic system fluid, reservoir or liquid lines throughout to maintain and purge daily
No hand tightened fittings
Easy service diagnostics
No remote syringes for liquid handling
No need for expensive 'black' tips to sense liquid levels

Advantages

over other air based systems

Actual volume measurement error handling as opposed to other systems that only report a clogged tip or short sample
Reduced liquid class development
No syringe seals to monitor

The Technology

Seyonic Sensor Controlled Pipetting systems provide accurate and precise liquid handling in the microliter to milliliter volume range. Operation is controlled through measurement of displaced air volumes by means of a flow sensor, integrated directly in the pipetting head, in connection with a high-speed solenoid valve.

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